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The liver is the body’s main detoxifying organ, therefore when a harmful substance such as synthetic drugs pass through, the liver can get damaged. Bahrke (2004) found that the adverse effects of anabolic steroids include liver damage, increased serum lipid levels, psychological disorders and reproductive system damage. Barhke also investigated the effects of two popular prohormones, androstenedione and DHEA, and concluded that there is no research indicating that these compounds significantly increases strength and/ or lean body mass in humans. These findings coincide with King (2005).
Radovanovic et al. (2003) investigated the effects of the steroid, methandienone. http://www.steroids-on-line.eu/Buy-Aromasin.html The researchers found increased activities of GDH, suggesting that anabolic steroids induce liver damage.
Velazquez (2004) found an association between the use of anabolic steroids, specifically oral antigens, and the incidence of liver tumors. The study concludes that all individuals on anabolic/ androgenic steroids are at risk for liver tumors, regardless of underlying diagnosis.
Steroid use is often anecdotally associated with libido changes and the shrinking of the male penis. These effects are not entirely accurate and often over-stated. For example, the male penis itself does not shrink in size, however in extreme cases the testicles may slightly shrink due to the reduction in sperm production. These symptoms are almost always temporary and will return at some point after steroid use has stopped. Karila (2004) found that the use of anabolic steroids impairs spermatogenesis both during and after steroid use.
Dohle (2003) found that the suppression of spermatogenesis by testosterone administration is the basis for the development of a male contraceptive. In other words, the use of anabolic steroids has been shown to adversely affect the fertility of males.
Anabolic steroids have been known to induce a condition in males known as priapism. Priapism is frequent and painful erections and can lead to considerable discomfort and even penile damage. The male testes also are greatly affected by steroid use. The testicles have been known to shrink while on a cycle due to the cessation of the production of endogenous testosterone. Athletes using Aromasin and multiple steroids for extended periods of time will see more dramatic changes in testicle size. Once endogenous testosterone production resumes, the testicles usually regain their normal size.
Bhasin et al. (2005) found that older athletes using steroids are more predisposed to side effects such as leg edema and prostate events.
Ho (2004) suggests that anabolic steroids may play an important role in urinary tract disorders.